Alcohol-and-HIV-Induced Lysosomal Dysfunction Regulates Extracellular Vesicles Secretion in Vitro and in Liver-Humanized Mice.
Raghubendra Singh DagurMoses New-AaronMurali GanesanWeimin WangSvetlana RomanovaSrivatsan KidambiKharbanda K KusumLarisa Y PoluektovaNatalia A OsnaPublished in: Biology (2021)
HIV-and-ethanol-metabolisminducedEVs release is tightly controlled by lysosome status in hepatocytes and participates in thedevelopment of double-insult-induced liver injury.
Keyphrases
- antiretroviral therapy
- hiv positive
- hiv infected
- hiv testing
- human immunodeficiency virus
- hepatitis c virus
- hiv aids
- men who have sex with men
- drug induced
- liver injury
- diabetic rats
- oxidative stress
- high glucose
- south africa
- monoclonal antibody
- high fat diet induced
- type diabetes
- fluorescent probe
- metabolic syndrome