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Inhaled endotoxin induces a systemic neutrophil response without affecting cardiovascular measures in a randomized cross-over exposure study.

Stephen A SchworerAlan L HinderliterMelissa C CaugheyCarole RobinetteKelly D ChasonHaolin LiHaibo ZhouAmika K SoodAllison J BurbankDavid B PedenMichelle L Hernandez
Published in: Inhalation toxicology (2024)
In healthy adults, systemic inflammation after LPS inhalation was not associated with acute changes in cardiovascular physiology. Larger studies are needed to investigate the effects of other PM components on inflammation induced cardiovascular dysfunction.
Keyphrases
  • oxidative stress
  • drug induced
  • liver failure
  • diabetic rats
  • inflammatory response
  • particulate matter
  • air pollution
  • cystic fibrosis
  • heavy metals
  • intensive care unit
  • case control
  • mechanical ventilation