Hippocampal subfield pathologic burden in Lewy body diseases vs. Alzheimer's disease.

David G CoughlinR IttyerahC PetersonJ S PhillipsS MillerK RascovskyD WeintraubA D SiderowfJ E DudaH I HurtigD A WolkC T McMillanP A YushkevichM GrossmanE B LeeJ Q TrojanowskiDavid John Irwin

Published in: Neuropathology and applied neurobiology (2020)

Our findings suggest that tau burden in hippocampal subfields may map closely with the distribution of SYN pathology in subfield CA2/3 in LBD diverging from traditional AD and contribute to episodic memory dysfunction in LBD.

Keyphrases

cerebral ischemia
neoadjuvant chemotherapy
cognitive decline
oxidative stress
parkinson disease
risk factors
temporal lobe epilepsy
working memory
locally advanced
cerebrospinal fluid
protein kinase
brain injury
radiation therapy
mild cognitive impairment
high density
blood brain barrier
rectal cancer