Interferon Kappa Is Up-Regulated in Psoriasis and It Up-Regulates Psoriasis-Associated Cytokines in vivo.

Yuanyuan LiYueqi SongLeqing ZhuXiao WangBin Yang Ping LuQuan ChenLianghua BinLiehua Deng

Published in: Clinical, cosmetic and investigational dermatology (2019)

Increased IFN-κ in psoriasis may be caused by injured cells-released nucleic acids, increased IFN-γ and self-activation. Its enhancement may contribute to the etiology of the disease by enhancing TNFA and IL17A gene expression.

Keyphrases

gene expression
dendritic cells
induced apoptosis
immune response
atopic dermatitis
nuclear factor
dna methylation
cell cycle arrest
signaling pathway
toll like receptor