New Advances in Cervical Cancer: From Bench to Bedside.
Ottavia D'OriaGiacomo CorradoAntonio Simone LaganàVito ChianteraEnrico VizzaAndrea GianniniPublished in: International journal of environmental research and public health (2022)
Cervical cancer is the most common gynecologic malignancy and the fourth most common cancer in women worldwide. Over the last two decades, minimally invasive surgery (MIS) has emerged as the mainstay in the surgical management of early-stage cervical cancer, bringing advantages such as a lower operative morbidity and shorter hospital stay compared to open surgery, while maintaining comparable oncologic outcomes in numerous retrospective studies. Considering oncological patients, it is mandatory to assess the oncological outcomes and safety of this type of surgery. Moreover, there are different future outlooks on cervical cancer therapy, based on immunotherapy, target therapy, and poly-ADP-ribose polymerases (PARP) inhibitors in combination with each other, and in combination with standard chemotherapy and radiotherapy. The goal is to find an approach that is as personalized as possible.
Keyphrases
- minimally invasive
- early stage
- rectal cancer
- robot assisted
- cancer therapy
- locally advanced
- coronary artery bypass
- radical prostatectomy
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- prostate cancer
- prognostic factors
- papillary thyroid
- drug delivery
- dna damage
- surgical site infection
- type diabetes
- radiation therapy
- emergency department
- polycystic ovary syndrome
- stem cells
- skeletal muscle
- squamous cell carcinoma
- acute coronary syndrome
- sentinel lymph node
- bone marrow
- young adults
- squamous cell
- oxidative stress
- mesenchymal stem cells
- weight loss
- endometrial cancer
- insulin resistance
- glycemic control
- electronic health record
- case control
- childhood cancer
- replacement therapy
- drug induced