Tuftsin-Bearing Liposomes Co-Encapsulated with Doxorubicin and Curcumin Efficiently Inhibit EAC Tumor Growth in Mice.

Kalaimathi MurugesanPadmapriya SrinivasanRaghunandan MahadevaChhitar M GuptaWahajul Haq

Published in: International journal of nanomedicine (2020)

In conclusion, we have developed a targeted liposomal formulation of P.Tuftsin-bearing liposomes co-encapsulated with effective anti-cancer drugs such as doxorubicin and curcumin. In experimental animals, tumor inhibition by P.Tuft-DOX-CUR LPs indicates the synergistic therapeutic effect of the peptide and the dual drug.

Keyphrases

drug delivery
cancer therapy
drug release
inflammatory response
high fat diet induced
drug induced
type diabetes
emergency department
skeletal muscle
insulin resistance