Bone-Marrow-Derived Mesenchymal Stem Cells, Their Conditioned Media, and Olive Leaf Extract Protect against Cisplatin-Induced Toxicity by Alleviating Oxidative Stress, Inflammation, and Apoptosis in Rats.
Mahrous Abdelbasset IbrahimAthar M KhalifaAlaa A MohamedRania A GalhomHoreya E KorayemNoha M Abd El-FadealAhmed Abd-Eltawab TammamMohamed Mansour KhalifaOsama S ElserafyRehab I Abdel-KarimPublished in: Toxics (2022)
These findings indicate that BM-MSC, CM-MSC, and OLE have beneficial effects in ameliorating cisplatin-induced oxidative stress, inflammation, and apoptosis in the hepatotoxicity, nephrotoxicity, immunotoxicity, and genotoxicity in a rat model.