Design and Applications of N-tert-Butyl Sulfinyl Squaramide Catalysts.

Yao LiCyndi Qixin HeFei-Xiang GaoZhen LiXiao-Song Xue Xin Li Kendall N Houk Jin-Pei Cheng

Published in: Organic letters (2017)

A new chiral HBD system, N-tert-butyl sulfinyl squaramide, was designed and synthesized. The core N-tert-butyl sulfinyl squaramide with an 1-aminoindan-2-ol skeleton was found to be an efficient catalyst in the enantioselective Friedel-Crafts alkylation of indoles and acyl phosphonates.

Keyphrases

highly efficient
ionic liquid
metal organic framework
room temperature
reduced graphene oxide
capillary electrophoresis
carbon dioxide
gold nanoparticles
oxide nanoparticles