Lysophosphatidic acid promotes ESCC progression by increasing the level of CCL2 secreted by esophageal epithelial cells.

Hui MaXiaoqian MaLingyu QiQian ZhangTiange WangQingdong GuoPeng LiShutian ZhangSi Liu

Published in: The journal of gene medicine (2024)

Our findings, taken together, demonstrate that CM from LPA-treated esophageal epithelial cells plays a significant role in promoting the progression of ESCC, with CCL2 acting as the primary regulator.

Keyphrases

liver fibrosis
liver injury
transcription factor
drug induced
newly diagnosed