Gram-negative bacillary meningitis in an immunocompetent adult.
Aniruddha RaySatyaki BasuSouradeep DasAtanu ChandraPublished in: BMJ case reports (2023)
Escherichia coli is a rare cause of community-acquired meningitis comprising about 1% of adult cases. However, it is a common pathogen in neonatal meningitis and in nosocomial setting (especially after penetrating craniocerebral injury or subsequent to neurosurgical procedures). We report a middle-aged woman, who was admitted with features of acute meningitis and subsequent investigations revealed E. coli growth in cerebrospinal fluid culture. The case is distinctive as no additional predisposing risk factors associated with gram-negative bacillary meningitis (traumatic brain injury, neurosurgical procedures, malignancy, immunosuppressive therapy, HIV infection, chronic alcoholism and diabetes) were present. She was treated with intravenous antibiotics as per sensitivity reports and discharged in clinically stable condition, without any residual neurological deficit.
Keyphrases
- cerebrospinal fluid
- gram negative
- multidrug resistant
- escherichia coli
- traumatic brain injury
- acinetobacter baumannii
- middle aged
- klebsiella pneumoniae
- type diabetes
- drug resistant
- healthcare
- cardiovascular disease
- emergency department
- liver failure
- mental health
- high dose
- single cell
- metabolic syndrome
- antiretroviral therapy
- glycemic control
- young adults
- cystic fibrosis
- newly diagnosed
- drug induced
- pseudomonas aeruginosa
- extracorporeal membrane oxygenation
- cell therapy
- acute respiratory distress syndrome
- smoking cessation
- low dose
- bone marrow