Utility of the Sonoclot analyzer to assess hyperfibrinolysis in dogs.
Yekaterina BurikoRebecka S HessJulie M PfeiferDeborah C SilversteinPublished in: Veterinary clinical pathology (2021)
The Sonoclot analyzer can be used to evaluate hyperfibrinolysis. Predictable changes were seen in the Sonoclot Signature and a decrease in PF and FTi was found with increasing tPA concentrations. The Sonoclot assay with a tPA concentration of 100 IU/mL is suggested a baseline measure of hyperfibrinolysis and has a resultant median FTi of 42 minutes, which is a practical time for clinical applications.
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