Endocardial Fibroelastosis is Secondary to Hemodynamic Alterations in the Chick Embryonic Model of Hypoplastic Left Heart Syndrome.

Zivorad PesevskiAlena KvasilovaTereza StopkovaOndrej NankaEliska Drobna KrejciChristine BuffintonRadka KockovaAdam EckhardtDavid Sedmera

Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2017)

Abnormal hemodynamic loading during heart development leads to myocardial hypoxia, stimulating collagen production in the subendocardium. Therefore, EFE in this chick embryonic model of HLHS appears to be a secondary effect of abnormal hemodynamics. Developmental Dynamics 247:509-520, 2018. © 2017 Wiley Periodicals, Inc.

Keyphrases

heart failure
atrial fibrillation
left ventricular
endothelial cells
case report