Neoadjuvant Chemotherapy and Immunotherapy in Luminal B-like Breast Cancer: Results of the Phase II GIADA Trial.

Maria Vittoria DieciValentina GuarneriAnna TosiGiancarlo BisagniAntonino MusolinoSimon SpazzapanGabriella MorettiGrazia Maria Vernaci Gaia Griguolo Tommaso GiarratanoLoredana UrsoFrancesca SchiaviClaudia PinatoGiovanna MagniMarcello Lo MeleGian Luca De Salvo Antonio Rosato PierFranco Conte

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)

Luminal B-like breast cancers with a Basal molecular subtype and/or a state of immune activation may respond to sequential anthracyclines and anti-PD-1. Our data generate hypotheses that, if validated, could guide immunotherapy development in this context.

Keyphrases

phase ii
neoadjuvant chemotherapy
clinical trial
open label
locally advanced
phase iii
lymph node
sentinel lymph node
placebo controlled
double blind
electronic health record
rectal cancer
study protocol
radiation therapy
childhood cancer