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Opportunistic Infections, Mortality Risk, and Prevention Strategies in Patients With Vacuoles, E1 Enzyme, X-Linked, Autoinflammatory, Somatic (VEXAS) Syndrome.

Mary CzechJennifer Cuellar-RodriguezBhavisha A PatelEmma M GroarkeEdward W CowenBenjamin TurturiceDavid B BeckLorena WilsonWendy GoodspeedIvana DardenNeal S YoungDennis HicksteinAmanda OmbrelloPatrycjia HoffmanEvsen Apaydin ArikanNinet SinaiiLonda HathawayLeslie Castelo-SoccioAlice FikeDaniel B KastnerPeter C GraysonMarcela A Ferrada
Published in: Open forum infectious diseases (2024)
Opportunistic infections are common in patients with VEXAS. Patients who develop PJP, HSV, or NTM are at increased risk for death. Prophylaxis against PJP and VZV is highly effective.
Keyphrases
  • copy number
  • gene expression
  • herpes simplex virus
  • dna methylation
  • genome wide