Auxiliary Medical Decision System for Prostate Cancer Based on Ensemble Method.
Jia WuQinghe ZhuangYanlin TanPublished in: Computational and mathematical methods in medicine (2020)
Prostate cancer (PCa) is one of the main diseases that endanger men's health worldwide. In developing countries, due to the large number of patients and the lack of medical resources, there is a big conflict between doctors and patients. To solve this problem, an auxiliary medical decision system for prostate cancer was constructed. The system used six relevant tumor markers as the input features and employed classical machine learning models (support vector machine and artificial neural network). Stacking method aimed at different ensemble models together was used for the reduction of overfitting. 1,933,535 patient information items had been collected from three first-class hospitals in the past five years to train the model. The result showed that the auxiliary medical system could make use of massive data. Its performance is continuously improved as the amount of data increases. Based on the system and collected data, statistics on the incidence of prostate cancer in the past five years were carried out. In the end, influence of diet habit and genetic inheritance for prostate cancer was analyzed. Results revealed the increasing prevalence of PCa and great negative impact caused by high-fat diet and genetic inheritance.
Keyphrases
- prostate cancer
- radical prostatectomy
- healthcare
- high fat diet
- machine learning
- neural network
- big data
- end stage renal disease
- ejection fraction
- insulin resistance
- risk factors
- public health
- type diabetes
- adipose tissue
- prognostic factors
- mental health
- case report
- deep learning
- mitochondrial dna
- copy number
- skeletal muscle
- convolutional neural network
- risk assessment
- patient reported
- wastewater treatment
- climate change
- middle aged
- medical students