Effect of Sodium-Glucose Cotransporter-2 Inhibitors on Endothelial Function: A Systematic Review of Preclinical Studies.

Afnan S AlshnbariSophie A MillarSaoirse E O'SullivanIskandar Idris

Published in: Diabetes therapy : research, treatment and education of diabetes and related disorders (2020)

Preclinical studies indicate that SGLT-2 inhibitors attenuate vascular dysfunction in preclinical models via a combination of mechanisms that appear to act independently of glucose-lowering benefits.

Keyphrases

cell therapy
case control
oxidative stress
stem cells
type diabetes
blood glucose
blood pressure
metabolic syndrome
skeletal muscle
adipose tissue
glycemic control