Intra-patient variability in tacrolimus exposure in pediatric liver transplant recipients: Evolution, risk factors, and impact on patient outcomes.
Charlotte DefrancqNika De WildeAnn RaesStephanie Van BiervlietSaskia Vande VeldeMyriam Van WinckelRuth De BruyneAgnieszka PrytułaPublished in: Pediatric transplantation (2019)
Our results highlight the impact of biological factors on TAC IPV during the early LT follow-up and later also therapy adherence. High TAC IPV may be associated with adverse patient outcomes.