Single-cell RNA sequencing reveals the multi-cellular ecosystem in different radiological components of pulmonary part-solid nodules.

Yanmeng LiXiao LiHaiming ChenKunkun SunHao LiYing ZhouJun WangFan BaiFan Yang

Published in: Clinical and translational medicine (2022)

The cellular landscape of ground-glass components is significantly different from that of normal tissue and similar to that of solid components. However, transcriptional differences exist in the vital signalling pathways of malignant and immune cells within these components.

Keyphrases

single cell
rna seq
climate change
pulmonary hypertension
gene expression
transcription factor
high throughput
oxidative stress
risk assessment