Immune response characterization of primary gingival fibroblasts from Grade C periodontitis patients.
Camila Schmidt StolfCatharina M SacramentoCarolina A P G AlvarengaJonathan R VieiraCássia F AraújoMabelle F MonteiroHélvis E S PazMauro P SantamariaKarina G S RuizRenato C V CasarinPublished in: Journal of periodontology (2022)
GFs from individuals with Perio4C tended to hypo-respond to stimulation with AaPE, producing lower concentrations of some pro- and anti-inflammatory molecules, trending to develop a pro-inflammatory extracellular environment.