Genome-wide Association Study Identifies 2 New Loci Associated With Anti-NMDAR Encephalitis.
Anja K TietzKlemens AngstwurmTobias BaumgartnerKathrin DopplerKatharina EisenhutMartin ElisakAndre FrankeKristin S GolombeckRobert HandrekaMax KaufmannMarkus KraemerAndrea KraftJan LewerenzWolfgang LiebMarie MadlenerNico MelzerHana MojzisovaPeter MöllerThomas PfefferkornHarald PrüssKevin RostásyMargret SchnegelsbergIna SchröderKai SiebenbrodtKurt-Wolfram SühsJonathan WickelKlaus-Peter WandingerChristian SchmidtGregor Kuhlenbäumernull nullPublished in: Neurology(R) neuroimmunology & neuroinflammation (2021)
This study provides evidence for relevant genetic determinants of antibody-mediated autoimmune encephalitides outside the human leukocyte antigen (HLA) region. The results suggest that future studies with larger sample sizes will successfully identify additional genetic determinants and contribute to the elucidation of the pathomechanism.