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Long-term Glycemic Control and Dementia Risk in Type 1 Diabetes.

Mary E LacyPaola GilsanzAndrew J KarterCharles P QuesenberryMark J PletcherRachel A Whitmer
Published in: Diabetes care (2018)
Among older patients with type 1 diabetes, those with majority exposure to HbA1c 8-8.9% and ≥9% had increased dementia risk, while those with majority exposure to HbA1c 6-6.9% and 7-7.9% had reduced risk. Currently recommended glycemic targets for older patients with type 1 diabetes are consistent with healthy brain aging.
Keyphrases
  • type diabetes
  • glycemic control
  • mild cognitive impairment
  • cardiovascular disease
  • insulin resistance
  • physical activity
  • metabolic syndrome
  • weight loss
  • multiple sclerosis
  • skeletal muscle
  • adipose tissue
  • resting state