Radiotherapy or Surgery of the Axilla After a Positive Sentinel Node in Breast Cancer: 10-Year Results of the Randomized Controlled EORTC 10981-22023 AMAROS Trial.
Sanne A L BartelsMila DonkerCoralie PoncetNicolas SauvéMarieke E StraverCornelis J H van de VeldeRobert E ManselCharlotte BlankenLorenzo OrzalesiJean H G KlinkenbijlHuub C J van der MijleGrard A P NieuwenhuijzenSanne C VeltkampThijs van DalenAndreas MarinelliHerman RijnaMarko SnojNigel J BundredJos W S MerkusYazid BelkacemiPatrick PetignatDominic A X SchinaglCorneel CoensGeertjan van TienhovenFrederieke H van DuijnhovenEmiel J T RutgersPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2022)
This 10-year analysis confirms a low ARR after both ART and ALND with no difference in OS, DFS, and locoregional control. Considering less arm morbidity, ART is preferred over ALND for patients with SN-positive cT1-2 breast cancer.
Keyphrases
- phase iii
- phase ii
- hiv infected
- minimally invasive
- open label
- double blind
- clinical trial
- early stage
- computed tomography
- lymph node
- coronary artery bypass
- antiretroviral therapy
- study protocol
- placebo controlled
- radiation therapy
- image quality
- contrast enhanced
- locally advanced
- radiation induced
- squamous cell carcinoma
- sentinel lymph node
- magnetic resonance
- breast cancer risk
- positron emission tomography
- acute coronary syndrome
- coronary artery disease
- atrial fibrillation
- percutaneous coronary intervention
- rectal cancer