A Novel Assessment of Metabolic Pathways in Peritoneal Metastases from Low-Grade Appendiceal Mucinous Neoplasms.

Eric A HanseTianhong WangDelia TifreaMaheswari SenthilAlex C KimMei KongOliver S Eng

Published in: Annals of surgical oncology (2023)

Distinct metabolic signatures may exist for PM from LAMN versus adenocarcinoma. A multitude of genes are differentially regulated, many of which are involved in metabolic pathways. Additional research is needed to identify the significance and applicability of targeting metabolic pathways in the potential development of novel therapeutics for these challenging tumors.

Keyphrases

low grade
high grade
genome wide
squamous cell carcinoma
air pollution
gene expression
small molecule
dna methylation
transcription factor
drug delivery
radiation therapy
cancer therapy
heavy metals