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Zuranolone therapy protects frontal cortex neurodevelopment and improves behavioral outcomes after preterm birth.

Roisin A MoloneyHannah K PalliserCarlton L PavyJulia C ShawJonathan J Hirst
Published in: Brain and behavior (2024)
This is the first study to assess zuranolone treatment as a neuroprotective therapy following preterm birth. Zuranolone treatment improved behavioral outcomes and structural changes in the preterm offspring, which continued long term until at least a late childhood timepoint. Clinical studies are warranted for further exploring the neuroprotective possibilities of this treatment following preterm birth.
Keyphrases
  • preterm birth
  • low birth weight
  • gestational age
  • type diabetes
  • metabolic syndrome
  • adipose tissue
  • preterm infants
  • bone marrow
  • mesenchymal stem cells
  • weight loss
  • early life