Comparative Efficacy of Avelumab Maintenance Therapy Versus Continued Chemotherapy Followed by Pembrolizumab in Metastatic Urothelial Carcinoma With No Progression After 4 Cycles of Chemotherapy: A Retrospective Study Using Propensity Score Matching.
Keita KobayashiHiroaki MatsumotoShigeru SakanoMitsutaka YamamotoMasahiro TsuchidaYasuhide TeiKazuhiro NagaoKazuo ObaSeiji KitaharaSeiji YanoSatoru YoshihiroYoshiaki YamamotoChietaka OhmiHirotaka KomatsuTaku MisumiJumpei AkaoKoji ShiraishiPublished in: Clinical genitourinary cancer (2024)
Progression-free survival was similar for avelumab maintenance therapy and the sequence of continued chemotherapy followed by pembrolizumab after no disease progression at four chemotherapy courses. Avelumab may require less high-dose glucocorticoid treatment, potentially enhancing safety.