A comparative study of platelet factor 4-enhanced platelet activation assays for the diagnosis of heparin-induced thrombocytopenia.

Julian G RubinoDonald M ArnoldTheodore Earl WarkentinJames W SmithJohn G KeltonIzhac Nazy

Published in: Journal of thrombosis and haemostasis : JTH (2021)

All PF4-enhanced assays demonstrated good performance characteristics when platelet donors were preselected. Further comparisons across multiple laboratories should be conducted for consensus on optimal HIT diagnostic testing.

Keyphrases

high throughput
venous thromboembolism
high glucose
diabetic rats
oxidative stress
clinical practice
endothelial cells