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Anodal Cerebellar Transcranial Direct Current Stimulation Reduces Motor and Cognitive Symptoms in Friedreich's Ataxia: A Randomized, Sham-Controlled Trial.

Gilles NaeijeAntonin RovaiVirginie DestrebecqNicolas TrottaXavier De Tiège
Published in: Movement disorders : official journal of the Movement Disorder Society (2023)
One week of treatment with anodal ctDCS reduces motor and cognitive symptoms in individuals with FRDA, likely by restoring the neocortical inhibition normally exerted by cerebellar structures. This study provides class I evidence that ctDCS stimulation is effective and safe in FRDA. © 2023 International Parkinson and Movement Disorder Society.
Keyphrases
  • transcranial direct current stimulation
  • working memory
  • double blind
  • high resolution
  • clinical trial
  • study protocol
  • open label
  • mass spectrometry
  • placebo controlled
  • depressive symptoms