The paradoxical changes of membrane and soluble herpes virus entry mediator in hepatocellular carcinoma patients.

Qi-Yi ZhaoGeng-Lin ZhangXiang ZhuDi SuZhan-Lian HuangZhao-Xia HuLiang Peng

Published in: Journal of gastroenterology and hepatology (2017)

Our data demonstrated paradoxical changes of membrane and soluble HVEM in the peripheral blood of HCC patients for the first time. These data supported the notion that roles of HVEM are likely to be immunosuppressive rather than activating tumor immunity. Future studies are warranted to further explore the translational values of mHVEM and sHVEM in peripheral blood as diagnostic markers and therapeutic targets.

Keyphrases

peripheral blood
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors
signaling pathway
machine learning
data analysis
artificial intelligence
case control