Energy Balance and Bone Health: a Nutrient Availability Perspective.
Beatriz BermudezToru IshiiYuan-Haw WuR Dana CarpenterVanessa D SherkPublished in: Current osteoporosis reports (2022)
The skeleton is a primary site for fatty acid and glucose uptake. The trafficking of carbohydrates and fats into tissues changes with weight loss and periods of weight gain. Exercise acutely influences nutrient uptake into bone and may affect nutrient partitioning to bone. Bone cells secrete hormones that signal to the brain and other tissues information about its energetic state, which may alter whole-body nutrient trafficking. There is a critical need for studies to address the changes that metabolic perturbations have on nutrient availability in bone.
Keyphrases
- bone mineral density
- weight gain
- weight loss
- bone loss
- soft tissue
- bone regeneration
- gene expression
- healthcare
- bariatric surgery
- induced apoptosis
- type diabetes
- body composition
- blood pressure
- cell death
- birth weight
- metabolic syndrome
- skeletal muscle
- health information
- high intensity
- cell proliferation
- climate change
- oxidative stress
- adipose tissue
- cell cycle arrest
- endoplasmic reticulum stress
- resistance training
- subarachnoid hemorrhage
- case control
- gestational age