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A clinical decision support tool may help to optimise vedolizumab therapy in Crohn's disease.

Parambir S DulaiAurelien AmiotLaurent Peyrin BirouletVipul JairathMelanie SerreroJerome FilippiSiddharth SinghBenjamin ParienteEdward V LoftusXavier RoblinSunanda KaneAnthony BuissonCorey A SiegelYoram BouhnikWilliam J SandbornKaren LaschMaria RosarioBrian G FeaganDaniela BojicCaroline Trang-PoissonBo ShenRomain AltweggBruce E SandsJean Frederic ColombelFranck Carbonnelnull null
Published in: Alimentary pharmacology & therapeutics (2019)
We further extended the clinical utility of a previously validated VDZ CDST, which accurately predicts at baseline exposure-efficacy relationships and rapidity of onset of action and could be used to help identify patients who would most benefit from interval shortening and those most likely to require surgery while on active therapy.
Keyphrases
  • clinical decision support
  • minimally invasive
  • electronic health record
  • acute coronary syndrome
  • ulcerative colitis
  • mesenchymal stem cells
  • coronary artery disease
  • atrial fibrillation
  • replacement therapy