An evaluation of the effect of lithium on taxane-induced neuropathy.

David C KochanPaul J NovotnyElizabeth J Cathcart-RakeJacob J OrmeAmye J TevaarwerkKathryn J RuddyDaniel S Childs

Published in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2023)

Targeted approaches for preventing CIPN are desperately needed. Despite sound scientific rationale, the current study did not identify neuroprotective properties of lithium.

Keyphrases

high glucose
cancer therapy
drug delivery
clinical trial
oxidative stress
endothelial cells
blood brain barrier
cerebral ischemia