DELIVER: A Safety Study of a Dapivirine Vaginal Ring and Oral PrEP for the Prevention of HIV During Pregnancy.

Katherine BungeJennifer E BalkusLee FairlieAshley J MayoClemensia NakabiitoNyaradzo MgodiLuis GadamaMoleen MatrimbiraCatherine Anne ChappellJeanna PiperNahida ChakhtouraDaniel W SzydloBarbra RichardsonSharon L Hillier

Published in: Journal of acquired immune deficiency syndromes (1999) (2023)

In this first study of a long-acting HIV prevention agent in pregnancy, adverse pregnancy outcomes and complications were uncommon when DVR and TDF/FTC were used in the third trimester of pregnancy, suggesting a favorable safety profile for both prevention products.

Keyphrases

pregnancy outcomes
pregnant women
preterm birth
hepatitis c virus
human immunodeficiency virus
antiretroviral therapy
risk factors
hiv aids
hiv testing
south africa
gestational age
electronic health record
adverse drug