A DNA Methylation-Based Test for Breast Cancer Detection in Circulating Cell-Free DNA.

Sofia Salta Sandra P NunesMário Fontes-SousaPaula LopesMicaela FreitasMargarida CaldasLuís AntunesFernando CastroPedro AntunesSusana Palma de SousaRui M Henrique Carmen Jerónimo

Published in: Journal of clinical medicine (2018)

This approach enables BrC accurate diagnosis and prognostic stratification in tissue samples, and allows for early detection in liquid biopsies, thus suggesting a putative value for patient management.

Keyphrases

dna methylation
case report
genome wide
gene expression
loop mediated isothermal amplification
high resolution
real time pcr
label free
ultrasound guided
copy number
mass spectrometry
breast cancer risk