Genetic engineering of hematopoiesis: current stage of clinical translation and future perspectives.

Published in: EMBO molecular medicine (2020)

Here I review the scientific background, current stage of development and future perspectives that I foresee in the field of genetic manipulation of hematopoietic stem cells with a special emphasis on clinical applications.

Keyphrases

stem cells
genome wide
copy number
bone marrow
dna methylation
gene expression
cell therapy