Integrative Analysis of Pleomorphic Dermal Sarcomas Reveals Fibroblastic Differentiation and Susceptibility to Immunotherapy.
Sebastian KleinAlexander QuaasKa-Won NohMaria CartolanoNima AbedpourCornelia MauchJennifer QuantiusHans Christian ReinhardtReinhard BuettnerMartin PeiferDoris HelbigPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
PDS is of fibroblastic differentiation and exhibits a strong susceptibility to immunotherapy, including a high mutational burden and an inflamed tumor microenvironment.