Functional Topography of the Human Subthalamic Nucleus: Relevance for Subthalamotomy in Parkinson's Disease.
Rafael Rodriguez-RojasJose A Pineda-PardoJorge Uriel Máñez-MiróAlicia Sanchez-TurelRaúl Martínez FernándezMarta Del AlamoMahlon DeLongJose A ObesoPublished in: Movement disorders : official journal of the Movement Disorder Society (2021)
Our results support an interplay between segregation and integration of cortico-subthalamic projections, suggesting the coexistence of parallel and convergent information processing. Identifying the functional topography of the STN will facilitate better definition of the optimal location for functional neurosurgical approaches, that is, electrode placement and lesion location, and improve specific cardinal features in PD. © 2021 International Parkinson and Movement Disorder Society.