Pretreatment Predictors of Very Poor Clinical Outcomes in Medium Vessel Occlusion Stroke Patients Treated with Mechanical Thrombectomy.
Vivek Srikar YedavalliHamza Adel SalimBasel MusmarNimer AdeebKareem El NaamaniNils HenningerSri Hari SundararajanAnna KuhnJane KhalifeSherief GhozyLuca ScarciaBenjamin Yong Qiang TanJeremy HeitRobert RegenhardtNicole Mariantonia CancelliereJoshua BernstockAymeric RouchaudJens FiehlerSunil A ShethMuhammed Amir EssibayiAjit S PuriChristian DyzmannMarco ColasurdoXavier BarreauLeonardo RenieriJoão Pedro FilipePablo HarkerRăzvan Alexandru RaduThomas MarrotaJulian SpearsTakahiro OtaAshkan MowlaPascal M JabbourArundhati BiswasFrederic ClarenconJames E SieglerThanh N NguyenRicardo VarelaAmanda BakerDavid AltschulNestor R GonzalezMarkus MöhlenbruchVincent CostalatBenjamin GoryChristian StrackeMohammad Ali Aziz-SultanConstantin HeckerHamza ShaikhDavid S LiebeskindAlessandro PedicelliAndrea Maria AlexandreIllario TancrediTobias D FaizyErwah KalsoumBoris LubiczAman B PatelVitor Mendes PereiraAdrien GuenegoAdam Andrew DmytriwPublished in: International journal of stroke : official journal of the International Stroke Society (2024)
This study demonstrates that advanced age, higher NIHSS scores, elevated pre-stroke mRS, and pre-operative glucose levels significantly predict very poor outcomes in AIS-MeVO patients who received MT. These findings highlight the importance of a comprehensive risk assessment in primary MeVO patients for personalized treatment strategies. However, they also suggest a need for cautious patient selection for endovascular thrombectomy. Further prospective studies are needed to confirm these findings and explore targeted therapeutic interventions.