Maternal insulin-like growth factors and insulin-like growth factor-binding proteins for macrosomia prediction in diabetic and nondiabetic pregnancy: A prospective study.

Elena N AlekseenkovaV N BabakovSergey A Selkov Gian Carlo Di Renzo Igor Yu Kogan Roman V Kapustin

Published in: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics (2023)

The authors detected different first-trimester IGF-1 and IGF-1/IGFBP-1 thresholds applicable for either supposition or rejection of macrosomia diagnosis. Further investigation is needed to determine how the maternal IGF axis can contribute to fetal macrosomia prediction.

Keyphrases

growth hormone
pregnancy outcomes
type diabetes
pi k akt
binding protein
birth weight
pregnant women
preterm birth
signaling pathway
glycemic control
cell proliferation
weight gain
gestational age
metabolic syndrome
body mass index
weight loss
insulin resistance