BRCA1 / 2 mutations in GI cancers: the risk to Pakistani families.

An article on the incidence of BReast CAncer gene 1 / 2 mutations in Pakistan to those of ovarian, breast, and other cancers, as well as their newly found association to gastrointestinal cancers, and the incidence and mortality rates of these malignancies. It involves a perspective on the epidemiological significance of BReast CAncer gene 1 / 2 mutations to various cancers and their immense risk to Pakistani families, as well as suggestions to tackle the problem, including possible advancement in their detection and treatment options to improve mortality rates.