Novel probe-based melting curve assays for the characterization of fluoroquinolone resistance in Mycoplasma genitalium.

Jacob A TicknerCatriona S BradshawGerald L MurrayDavid M WhileyEmma L Sweeney

Published in: The Journal of antimicrobial chemotherapy (2022)

These proof-of-concept assays have considerable potential to improve individualized treatment approaches and rationalize tests of cure for M. genitalium infection. The ability to initiate individualized treatment in up to two-thirds of cases will enhance antimicrobial stewardship for this challenging pathogen.

Keyphrases

high throughput
high resolution
combination therapy
mass spectrometry
living cells
climate change