The Inhibitory Effects of Gold Nanoparticles on VEGF-A-Induced Cell Migration in Choroid-Retina Endothelial Cells.

Chi-Ming ChanChien-Yu HsiaoHsin-Ju LiJia-You FangDer-Chen ChangChi-Feng Hung

Published in: International journal of molecular sciences (2019)

These results suggest that AuNPs are an effective inhibitor of VEGF-induced RF/6A cell migration through the Akt/eNOS pathways, but they have no effects on their cell viabilities and cell adhesion to fibronectin.

Keyphrases

cell migration
endothelial cells
high glucose
gold nanoparticles
cell adhesion
vascular endothelial growth factor
diabetic rats
drug induced
cell proliferation
signaling pathway
oxidative stress
bone marrow
nitric oxide
pi k akt
nitric oxide synthase
type iii
mesenchymal stem cells