Ceramide changes in abdominal subcutaneous and visceral adipose tissue among diabetic and nondiabetic patients.
Michelle BrusatoriMichael H WoodStephanie C TuckerKrishna Rao MaddipatiS Kiran KoyaGregory W AunerKenneth V HonnBerhane SeyoumPublished in: Journal of diabetes (2022)
Analysis of ceramides is important for developing a better understanding of biological processes underlying type 2 diabetes, metabolic syndrome, and obesity. Knowledge of the accumulated ceramides/dihydroceramides may reflect on the prelipolytic state that leads the lipotoxic phase of insulin resistance and may shed light on the predisposition to insulin resistance by gender.
Keyphrases
- insulin resistance
- metabolic syndrome
- adipose tissue
- type diabetes
- high fat diet
- high fat diet induced
- skeletal muscle
- polycystic ovary syndrome
- end stage renal disease
- glycemic control
- ejection fraction
- healthcare
- chronic kidney disease
- newly diagnosed
- cardiovascular disease
- prognostic factors
- peritoneal dialysis
- patient reported outcomes
- body mass index