Number needed to treat with ursodeoxycholic acid therapy to prevent liver transplantation or death in primary biliary cholangitis.
Maren H HarmsRozanne C de VeerWillem J LammersChristophe CorpechotDouglas ThorburnHarry L A JanssenKeith D LindorPalak J TrivediGideon M HirschfieldAlbert ParesAnnarosa FloreaniMarlyn J MayoPietro InvernizziPier Maria BattezzatiFrederik NevensCyriel Y PonsioenAndrew L MasonKris V KowdleyBettina E HansenHenk R van BuurenAdriaan J van der MeerPublished in: Gut (2019)
The absolute clinical efficacy of UDCA with respect to LT or death varied with baseline prognostic characteristics, but was high throughout. These findings strongly emphasise the incentive to promptly initiate UDCA treatment in all patients with PBC and may improve patient compliance.