Infectious complications of vascular anomalies treated with sirolimus: A systematic review.

Rachel KalbfellSally Cohen-CutlerEric GrishamChristine BereitschaftAlexandra J BorstAbby M GreenDaniel N WillisLauren YaegerJulie Blatt Bryan A Sisk

Published in: Pediatric blood & cancer (2023)

Most infectious complications reported in patients with VA on mTOR inhibitors were viral respiratory infections and non-severe. Bacteremia, infectious fatalities, and PJP are exceedingly rare. Future studies are needed to clarify the spectrum of infectious risks in VA patients and to provide guidance for infection prevention.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
risk factors
prognostic factors
sars cov
risk assessment
current status
human health
multidrug resistant