Telmisartan attenuates kidney apoptosis and autophagy-related protein expression levels in an intermittent hypoxia mouse model.

Xiao-Bin ZhangJing-Huang CaiYu-Yun YangYi-Ming ZengHui-Qing ZengMiao WangXiao ChengXiongbiao LuoHenry Chidozie Ewurum

Published in: Sleep & breathing = Schlaf & Atmung (2018)

The CIH accelerates renal apoptosis and autophagy levels. Telmisartan ameliorating those levels suggests that it might prevent renal impairs from the CIH in OSA patients.

Keyphrases

endoplasmic reticulum stress
cell death
oxidative stress
mouse model
end stage renal disease
cell cycle arrest
ejection fraction
signaling pathway
chronic kidney disease
newly diagnosed
obstructive sleep apnea
prognostic factors
patient reported outcomes
drug induced