Oxidative stress does not contribute to the release of proinflammatory cytokines through activating the Nod-like receptor protein 3 inflammasome in patients with obstructive sleep apnoea.
Tingyu TangQingdong HuangJuan LiuXiaoxi ZhouJianzong DuHaiyan WuZhijun LiPublished in: Sleep & breathing = Schlaf & Atmung (2018)
The current study suggests that oxidative stress leads to inflammation by mechanisms other than activation of the NLRP3 inflammasome in OSA patients. Furthermore, both sleep apnoea and BMI influenced the serum concentration of inflammatory mediators.
Keyphrases
- oxidative stress
- nlrp inflammasome
- positive airway pressure
- end stage renal disease
- dna damage
- ischemia reperfusion injury
- newly diagnosed
- chronic kidney disease
- ejection fraction
- diabetic rats
- physical activity
- induced apoptosis
- obstructive sleep apnea
- body mass index
- signaling pathway
- prognostic factors
- peritoneal dialysis
- binding protein
- heat shock
- weight gain
- amino acid
- sleep apnea
- endoplasmic reticulum stress
- patient reported
- heat stress