Systematic Evaluation of Clinical, Nutritional and Fecal Microbial Factors for their Association with Colorectal Polyps.
David SchultH Carlo MaurerMarina FrolovaMarc RingelhanUlrich MayrJörg UlrichMarkus HeilmaierSebastian RaschTobias LahmerSandra ReitmeierChiara HennigChristina GassnerNiklas ThurTheresa WillKlaus-Peter JanssenKatja SteigerMoritz JesinghausKlaus NeuhausMichael QuanteDirk HallerMohamed AbdelhafezRoland M SchmidMoritz MiddelhoffPublished in: Clinical and translational gastroenterology (2023)
We show for the first time an increased AP in premalignant CP. Furthermore, AP showed a significant influence on the microbial composition of the intestine. Relatively elevated liver enzymes, especially AP, may contribute to the detection of precancerous dysplastic or neoplastic changes in colorectal lesions. The association between elevated AP, premalignant CP, and the microbiome merits further study.
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