Allogeneic stem cell transplant in myelodysplastic syndrome-factors impacting survival.

Shruti PremEshetu G AtenafuWilson LamArjun LawFotios V MichelisDennis KimAuro ViswabandyaJeffrey Howard LiptonJonas MattssonRajat Kumar

Published in: European journal of haematology (2019)

Our results highlight the importance of karyotype on survival after allo-HCT and identify serum ferritin and transfusion dependence as important surrogate markers of outcome. In addition, our results demonstrate the efficacy of azacytidine for pretransplant cytoreduction.

Keyphrases

stem cells
stem cell transplantation
bone marrow
cardiac surgery
hematopoietic stem cell
free survival
sickle cell disease
cell cycle arrest
high dose
low dose
cell proliferation
signaling pathway