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New Myrtenal-Adamantane Conjugates Alleviate Alzheimer's-Type Dementia in Rat Model.

Stela DragomanovaMaria LazarovaAldar A MunkuevEvgenii V SuslovKonstantin P VolchoNariman SalakhutdinovAmina BibiJóhannes ReynissonElina TzvetanovaAlbena AlexandrovaAlmira GeorgievaDiamara UzunovaMiroslava StefanovaReni KalfinLyubka Tancheva
Published in: Molecules (Basel, Switzerland) (2022)
For the first time, neuroprotective properties of two MACs in a rat dementia model were observed. They were stronger than the natural M effects, which makes the substances promising candidates for AD treatment.
Keyphrases
  • mild cognitive impairment
  • cognitive decline
  • cognitive impairment
  • oxidative stress
  • drinking water
  • cerebral ischemia
  • blood brain barrier
  • smoking cessation