Longitudinal ellipsoid zone and subretinal fluid mapping following ocriplasmin injection in the prospective observational ORBIT trial.

Jeremy A LavineSunil K SrivastavaNeeley DuklesJamie L ReeseJustis P Ehlers

Published in: The British journal of ophthalmology (2019)

Ocriplasmin treatment resulted in VMT release, MH closure and visual acuity gains in a significant portion of eyes. EZ volume was significantly reduced at week 1, but recovered to baseline levels by final follow-up and was not associated with final visual acuity.

Keyphrases

clinical trial
study protocol
optical coherence tomography
high resolution
phase iii
phase ii
high density
combination therapy
open label
replacement therapy